Drug Repurposing by Simulating Flow Through Protein-Protein Interaction Networks
نویسندگان
چکیده
منابع مشابه
Drug Repurposing by Simulating Flow Through Protein–Protein Interaction Networks
As drug development is extremely expensive, the identification of novel indications for in-market drugs is financially attractive. Multiple algorithms are used to support such drug repurposing, but highly reliable methods combining simulation of intracellular networks and machine learning are currently not available. We developed an algorithm that simulates drug effects on the flow of informati...
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ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 2017
ISSN: 0009-9236
DOI: 10.1002/cpt.769